ABSTRACT
Background: As depression is one of the common diseases in the world and because of the lack of proper response via usual medications, using electromagnet fields [EMF], as an alternative treatment, has become noticeable. Thus, in the present study, the effect of EMF with low frequencies was investigated on the treatment of depression
Materials and methods: The experimental study was carried out on 32 male mice [albino, mean weight of 30g] after their adaptation in animal house. The animals were classified into 4 groups [n=8]. All 4 groups were injected with high dose of reserpine [5 mg/kg] i.p. and from those, 3 groups exposed with EMF [10, 25, and 50 HZ frequencies, respectively, with intense 250 micro T] for one week, 30 minutes daily. In all 3 groups, the signs of depression [sedation, righting reflexes and swimming], diarrhea, eyes hemorrhage, and feet and hands hemorrhage were observed and compared with control group [those without exposing to EMFs]
Results: Reserpine-induced depression caused sedation, righting reflex disorders, swimming difficulty, diarrhea and eye bleeding. The sedation in 10 and 25 HZ was significantly decreased. EMF in all frequencies decreased sings significantly, particularly in 25 HZ frequency. In swimming, EMF with 10 Hz was the most effective frequency
Conclusion: The findings showed that using EMES in low frequency can reduce most signs of reserpine-induced depression
ABSTRACT
The application of CAM visual stimulation returns to the date of more than fifty years ago. However, the reports of previous studies in this field vary from no effect to significant effects of this method in amblyopia treatment. The purpose of this study was to determine the effect of CAM visual stimulation along with conventional occlusion therapy in anisometropic amblyopic children. Forty amblyopic children aged 4 to 6 years old with no previous treatment were enrolled in this randomized clinical trial study. The subjects were randomly assigned in two different groups. The group 1 included conventional occlusion therapy and group 2 includes occlusion therapy with complementary CAM visual stimulation. In terms of visual acuity and stereopsis improvement and reduction of amblyopia severity, two groups were compared using the repeated measure ANOVA and LSD Post Hoc tests. In group 1 including conventional occlusion therapy, visual acuity improved from 0.444 +/- 0.077 logMAR to 0.138 +/- 0.023 logMAR, i.e., improvement of 0.306 logMAR [P<0.001] whereas in group 2 including complementary CAM usage, visual acuity improved from 0.398 +/- 0.075 logMAR to 0.047 +/- 0.022 logMAR, i.e., improvement of 0.351 logMAR [P<0.001]. Regarding Stereopsis, the improvements were 157 [from 258 +/- 34 to 101 +/- 13 seconds of arc, P<0.001] and 171 [from 237 +/- 33 to 66 +/- 12 seconds of arc, P<0.001] for groups 1 and 2 respectively. All subjects of group 2 gained the normal vision at the end of the treatment period, whereas only 47% of subjects of group 1 could achieve this level of vision in that time. Improvement of visual acuity in group 2 was significantly better than group 1 [P<0.05]. Using of CAM visual stimulation along with conventional occlusion will further improve visual acuity and stereopsis in amblyopic children. These findings recommended the CAM visual stimulation as an accompanying and complementary method in amblyopia treatment